Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BCL6 | P41182 | 2/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032290 | 0.84 | MAPT (0.50) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4837520 | 0.75 | EHMT2 (0.49) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4838322 | 0.75 | BCL6 (0.57) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4838816 | 0.75 | BCL6 (0.65) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL27628433 | 0.71 | BCL6 (0.55) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL14294052 | 0.70 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4832649 | 0.70 | BCL6 (0.49) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4832415 | 0.70 | BCL6 (0.56) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4837970 | 0.69 | MEN1 (0.52) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4870953 | 0.69 | BCL6 (0.55) | MAPTMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335656-B2 | Stent with a disposed traiazine compound such as 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4-diamine for inhibiting smooth muscle proliferation; restenosis and atherosclerosis | REDDY US THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | claimed |