Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700603 | 0.73 | NPC1 (0.39) | NPC1 | |
| SCHEMBL28449701 | 0.72 | — | — | |
| SCHEMBL5031087 | 0.70 | CA1 (0.33) | NPC1CA1CA2 | |
| SCHEMBL28713054 | 0.70 | NPC1 (0.35) | NPC1 | |
| SCHEMBL28963148 | 0.69 | CA1 (0.36) | NPC1CA1CA2 | |
| SCHEMBL28962625 | 0.66 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL5031045 | 0.65 | NPC1 (0.36) | NPC1 | |
| SCHEMBL1683314 | 0.65 | CA1 (0.33) | NPC1CA1CA2 | |
| SCHEMBL9813280 | 0.65 | CA1 (0.33) | NPC1CA1CA2 | |
| SCHEMBL9623348 | 0.65 | CA1 (0.33) | NPC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |