⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL489057 | 1.00 | — | — | |
| Hydrogen Sulfide SCHEMBL11329373 | 1.00 | — | — | |
| Hydrogen Sulfide SCHEMBL1191592 | 0.95 | — | — | |
| SCHEMBL21327 | 0.94 | — | — | |
| SCHEMBL2471012 | 0.94 | — | — | |
| Hydrogen Sulfide SCHEMBL2990550 | 0.91 | — | — | |
| SCHEMBL20481575 | 0.89 | — | — | |
| SCHEMBL10749569 | 0.89 | — | — | |
| SCHEMBL20787983 | 0.89 | — | — | |
| SCHEMBL20640191 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257573-B1 | IMPROVED CONTROLLED RADICAL POLYMERIZATION PROCESSES | UNIV CARNEGIE MELLON (US) | 2019-06-26 | — | — | EP | claimed |
| US-8445610-B2 | Controlled radical polymerization processes | CARNEGIE MELLON UNIVERSITY (US) | 2013-05-21 | — | — | US | claimed |
| US-20110046324-A1 | IMPROVED CONTROLLED RADICAL POLYMERIZATION PROCESSES | MATYJASZEWSKI KRZYSZTOF | 2011-02-24 | — | — | US | claimed |
| EP-2257573-A1 | IMPROVED CONTROLLED RADICAL POLYMERIZATION PROCESSES | Carnegie Mellon University (US) | 2010-12-08 | — | — | EP | claimed |
| US-20090317357-A1 | Methods for treating or preventing autoimmune disease using histamine h1 receptor-blocking agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-24 | — | — | US | claimed |
| WO-2009111725-A1 | IMPROVED CONTROLLED RADICAL POLYMERIZATION PROCESSES | CARNEGIE MELLON UNIVERSITY (US) | 2009-09-11 | — | — | WO | claimed |
| US-20070232692-A1 | Method of Treating Cancer Using Dithiocarbamate Derivatives | THE UNIVERSITY OF UTAH | 2007-10-04 | — | — | US | claimed |
| WO-2004075845-A2 | METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASE USING HISTAMINE H1 RECEPTOR-BLOCKING AGENTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-09-10 | — | — | WO | claimed |
| WO-2003099784-A1 | METHOD FOR PREPARATION OF PHARMACEUTICAL-GRADE DISULFIDE OF DITHIOCARBAMATES | MEDINOX, INC. (US) | 2003-12-04 | — | — | WO | claimed |
| US-20030181495-A1 | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor | MEDINOX, INC. | 2003-09-25 | — | — | US | claimed |
| US-6596770-B2 | Disulfide derivative of a dithiocarbamate is coadministered with an agent that inactivates (or inhibits the production of)the species that induce the expression of nitric oxide synthase | MEDINOX, INC. | 2003-07-22 | — | — | US | claimed |
| US-6596733-B2 | Nitric oxide scavengers, such as dithiocarbamate-containing compounds, are used to reduce side effects caused by therapeutical administration of nitric oxide sources | MEDINOX, INC. | 2003-07-22 | — | — | US | claimed |
| EP-1089723-A4 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | MEDINOX INC (US) | 2003-07-16 | — | — | EP | claimed |
| US-20020151540-A1 | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor | MEDINOX, INC. | 2002-10-17 | — | — | US | claimed |
| CN-1315856-A | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor | MEDINOX INC (US) | 2001-10-03 | — | — | CN | claimed |
| EP-1089723-A1 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | Medinox, Inc. (US) | 2001-04-11 | — | — | EP | claimed |
| WO-1999066918-A9 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | MEDINOX INC (US) | 2000-03-30 | — | — | WO | claimed |
| WO-1999066918-A1 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | MEDINOX, INC. (US) | 1999-12-29 | — | — | WO | claimed |
| JP-9111273-A | — | — | None | — | — | JP | disclosed |
| US-4618461-A | O,O'-, O,S'- or S,S'-dithiodialkylene-bis(mono- or dihydrocarbyl carbamothioates) and S,S'-dithiodialkylene-bis(mono- or dihydrocarbyl carbamodithioates) and method of preparation thereof | THE DOW CHEMICAL COMPANY (US) | 1986-10-21 | — | — | US | disclosed |