⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561916 | 0.92 | — | — | |
| SCHEMBL11410461 | 0.92 | — | — | |
| SCHEMBL9561906 | 0.92 | — | — | |
| SCHEMBL3022354 | 0.75 | — | — | |
| Aminomethyl(Hydroxymethyl)Phosphinic Acid SCHEMBL9313191 | 0.74 | — | — | |
| SCHEMBL2482866 | 0.74 | — | — | |
| SCHEMBL215192 | 0.73 | — | — | |
| SCHEMBL20913005 | 0.73 | CYP1A2 (0.39) | — | |
| SCHEMBL31331499 | 0.72 | — | — | |
| Water SCHEMBL11452217 | 0.70 | KDM4E (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458067-A1 | Process for the preparation of bis(hydroxymethyl)phosphinic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-27 | — | — | EP | claimed |
| JP-4226997-A | — | — | None | — | — | JP | disclosed |
| US-20080146708-A1 | phosphorus compounds used as flame retardants, binders, curing agents, light or heat stabilizers, plant safening agents, herbicides, pesticides, fungicides, drug and petroleum adjuvants, enzyme modulators, sequestering agents, corrosion and oxidation inhibitors, decolorizers and free radical scavengers | CLARIANT INTERNATIONAL LTD. | 2008-06-19 | — | — | US | disclosed |
| US-5196554-A | Reacting metal phosphinate and formaldehyde, trioxane, or paraformaldehyde in water; autoclaving | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| US-5196554-A | Reacting metal phosphinate and formaldehyde, trioxane, or paraformaldehyde in water; autoclaving | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| JP-H04226997-A | PRODUCTION OF ALUMINUM-BIS(HYDROXYMETHYL)PHOSPHINATE AND BIS(HYDROXYMETHYL)PHOSPHINATE | HOECHST AG | 1992-08-17 | — | — | JP | disclosed |
| EP-0458067-A1 | Process for the preparation of bis(hydroxymethyl)phosphinic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-27 | — | — | EP | disclosed |
| EP-0458067-A1 | Process for the preparation of bis(hydroxymethyl)phosphinic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-27 | — | — | EP | disclosed |