Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597303 | 0.89 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL3597299 | 0.89 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL5037341 | 0.88 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL5037343 | 0.88 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL3584108 | 0.87 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL3584105 | 0.87 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL3579650 | 0.85 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL3579645 | 0.85 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL3589487 | 0.83 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL3595980 | 0.83 | TRPV1 (0.48) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954132-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007100758-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-09-07 | — | — | WO | claimed |