SCHEMBL5032267

SCHEMBL5032267

Cl[SiH](Cl)OCCOc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.56
PKM P14618 2/20 0.52
ALDH1A1 P00352 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
RECQL P46063 1/20 0.50
HTR1B P28222 2/20 0.45
DRD2 P14416 2/20 0.45
DRD4 P21917 2/20 0.45
DRD3 P35462 2/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11234011 0.82 KCNA3 (0.61) KCNA3PKMALDH1A1TAAR1RECQL
SCHEMBL5032252 0.82 KCNA3 (0.48) KCNA3PKMALDH1A1TAAR1RECQL
SCHEMBL27962 0.81 KCNA3 (0.82) KCNA3PKMALDH1A1TAAR1RECQL
SCHEMBL5395774 0.78 KCNA3 (0.56) KCNA3PKMALDH1A1TAAR1RECQL
SCHEMBL5382089 0.77 KCNA3 (0.54) KCNA3PKMALDH1A1TAAR1RECQL
SCHEMBL11220222 0.77 KCNA3 (0.54) KCNA3PKMALDH1A1TAAR1RECQL
Ethylene SCHEMBL29058163 0.76 KCNA3 (0.74) KCNA3PKMALDH1A1TAAR1RECQL
SCHEMBL28659936 0.75 KCNA3 (0.52) KCNA3PKMALDH1A1TAAR1RECQL
SCHEMBL4156205 0.75 KCNA3 (0.64) KCNA3PKMALDH1A1TAAR1RECQL
SCHEMBL11087417 0.74 KCNA3 (0.70) KCNA3PKMALDH1A1TAAR1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed