Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8229034 | 1.00 | DPP4 (1.00) | DPP4DPP8CYP3A4 | |
| SCHEMBL3392452 | 1.00 | DPP4 (1.00) | DPP4DPP8CYP3A4 | |
| SCHEMBL3388710 | 0.88 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL3388711 | 0.88 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL3388714 | 0.88 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL3390501 | 0.86 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL3390500 | 0.86 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL204349 | 0.84 | DPP4 (1.00) | DPP4DPP8CYP3A4 | |
| SCHEMBL204350 | 0.84 | DPP4 (1.00) | DPP4DPP8CYP3A4 | |
| SCHEMBL27875485 | 0.84 | DPP4 (1.00) | DPP4DPP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506967-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2007-11-21 | — | — | EP | claimed |
| EP-1911754-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2013-10-09 | — | — | EP | disclosed |
| EP-1911754-A1 | Dipeptidyl peptidase inhibitors | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |