Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | EYA2 | O00167 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345486 | 1.00 | TDP1 (0.31) | TDP1EYA2APPACEMEN1 | |
| SCHEMBL4564930 | 1.00 | TDP1 (0.31) | TDP1EYA2APPACEMEN1 | |
| SCHEMBL12202775 | 0.95 | — | — | |
| SCHEMBL12202789 | 0.95 | — | — | |
| SCHEMBL3498361 | 0.94 | TDP1 (0.33) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL3844876 | 0.90 | EPOR (0.33) | TDP1EYA2APPACEMEN1 | |
| SCHEMBL12694735 | 0.88 | TDP1 (0.33) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL8058792 | 0.86 | CYP2D6 (0.35) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL6511739 | 0.86 | CYP2D6 (0.35) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL5033034 | 0.83 | MEN1 (0.34) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935435-B1 | Blood pool agents for nuclear magnetic resonance diagnostics | BRACCO IMAGING SPA (IT) | 2017-09-06 | — | — | EP | disclosed |
| EP-1140209-B1 | BLOOD POOL AGENTS FOR NUCLEAR MAGNETIC RESONANCE DIAGNOSTICS | BRACCO IMAGING SPA (IT) | 2008-08-20 | — | — | EP | disclosed |
| EP-1935435-A2 | Blood pool agents for nuclear magnetic resonance diagnostics | Bracco Imaging S.p.A (IT) | 2008-06-25 | — | — | EP | disclosed |