Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6981197 | 0.98 | FFAR1 (0.63) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL11131388 | 0.94 | FFAR1 (0.59) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL11132309 | 0.90 | SRD5A2 (0.61) | FFAR1KEAP1CA1CA2FFAR4 | |
| Hydrochloric Acid SCHEMBL11132121 | 0.89 | SRD5A2 (0.59) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL69746 | 0.88 | FFAR1 (0.81) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL11132034 | 0.87 | FFAR1 (0.52) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL11007974 | 0.87 | SMN1; SMN2 (0.67) | FFAR1KEAP1CA1CA2LMNA | |
| SCHEMBL4845038 | 0.86 | FFAR1 (0.65) | FFAR1KEAP1CA1CA2FFAR4 | |
| Hydrochloric Acid SCHEMBL11136747 | 0.86 | FFAR1 (0.50) | FFAR1KEAP1CA1CA2FFAR4 | |
| Hydrochloric Acid SCHEMBL25264643 | 0.85 | FFAR1 (0.77) | FFAR1KEAP1CA1CA2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986789-A | Hydroquinone compound and preparation method thereof and the application in antitumor or immunological regulation | 中国人民解放军军事医学科学院生物医学分析中心 | 2017-07-28 | — | — | CN | claimed |
| CN-116368131-B | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-116368131-A | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116253724-A | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2023-06-13 | — | — | CN | disclosed |
| WO-2023102077-A1 | ANTI-FOLATE RECEPTOR CONJUGATE CANCER THERAPY | SUTRO BIOPHARMA, INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| EP-4074728-A1 | MODIFIED PEPTIDES COMPRISING AN AZIDO GROUP | Sutro Biopharma, Inc. (US) | 2022-10-19 | — | — | EP | disclosed |
| WO-2022148459-A1 | CLASS OF NOVEL SMAD3 PROTEIN DEGRADERS AND APPLICATION THEREOF | 和径医药科技（上海）有限公司 | 2022-07-14 | — | — | WO | disclosed |
| WO-2022103983-A9 | FLUORENYLMETHYLOXYCARBONYL AND FLUORENYLMETHYLAMINOCARBONYL COMPOUNDS, PROTEIN CONJUGATES THEREOF, AND METHODS FOR THEIR USE | SUTRO BIOPHARMA, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022103983-A2 | FLUORENYLMETHYLOXYCARBONYL AND FLUORENYLMETHYLAMINOCARBONYL COMPOUNDS, PROTEIN CONJUGATES THEREOF, AND METHODS FOR THEIR USE | SUTRO BIOPHARMA, INC. (US) | 2022-05-19 | — | — | WO | disclosed |
| EP-3584255-B1 | MODIFIED AMINO ACIDS COMPRISING AN AZIDO GROUP | SUTRO BIOPHARMA INC (US) | 2022-02-16 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |
| CN-1124250-A | 17-deoxycorticosteroid-21-[O]-carboxylic esters, processes for their preparation and pharmaceuticals containing these compounds | HOECHST AG (DE) | 1996-06-12 | — | — | CN | disclosed |
| CN-1108661-A | Corticoid 17,21-dicarboxylic esters and corticosteroid 17-carboxylic ester 21-carbonic esters, processes for their preparation and pharmaceuticals containing these compounds | HOECHST AG (DE) | 1995-09-20 | — | — | CN | disclosed |
| CN-1105368-A | Corticosteroid 17-alkyl carbonate 21-[O]-carboxylic and carbonic esters, processes for their preparation, and pharmaceuticals containing these compounds | HOECHST AG (DE) | 1995-07-19 | — | — | CN | disclosed |
| EP-0181592-B1 | USE OF SPERGUALIN DERIVATIVES FOR THE PREPARATION OF MEDICAMENTS HAVING IMMUNOSUPPRESSIVE ACTIVITY | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1992-09-16 | — | — | EP | disclosed |
| CN-1005150-B | 1, 5-benzothiazepine * derivatives as platelet aggregation inhibitors | 田道制药株式会社 | 1989-09-13 | — | — | CN | disclosed |
| US-4851446-A | SPERGUALIN-LIKE GUANIDINES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0181592-A2 | Use of spergualin derivatives for the preparation of medicaments having immunosuppressive activity | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1986-05-21 | — | — | EP | disclosed |
| EP-0131445-A2 | Polyphenylene ether resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-01-16 | — | — | EP | disclosed |
| US-3996201-A | MOLDING | CIBA-GEIGY CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |