Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068250 | 0.81 | — | — | |
| SCHEMBL35398 | 0.76 | — | — | |
| SCHEMBL989057 | 0.75 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL10648386 | 0.75 | TP53 (0.31) | TP53 | |
| SCHEMBL1375064 | 0.75 | — | — | |
| SCHEMBL261633 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL4372441 | 0.72 | — | — | |
| SCHEMBL2657151 | 0.71 | — | — | |
| SCHEMBL1517603 | 0.70 | — | — | |
| SCHEMBL610415 | 0.70 | MEN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794621-B1 | NOVEL ORGANOSILICA COMPOUNDS | UNIV GENT (BE) | 2018-09-26 | — | — | EP | claimed |
| US-9181282-B2 | Organosilica compounds | UNIVERSITEIT GENT (BE) | 2015-11-10 | — | — | US | claimed |
| US-20150005525-A1 | NOVEL ORAGNOSILICA COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-01 | — | — | US | claimed |
| EP-2794621-A1 | NOVEL ORGANOSILICA COMPOUNDS | Universiteit Gent (BE) | 2014-10-29 | — | — | EP | claimed |
| WO-2013093022-A1 | NOVEL ORGANOSILICA COMPOUNDS | UNIVERSITEIT GENT (BE) | 2013-06-27 | — | — | WO | claimed |
| CN-114133360-A | Fluorine-containing benzo [ d ] -1, 3-oxazepine compound and synthetic method thereof | 南京工业大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-109369584-A | A kind of 2- aryl groups per alkyl group -3- (substituted olefine) aphthofurans derivative and its synthetic method | 华东师范大学 | 2019-02-22 | — | — | CN | disclosed |
| EP-2794621-B1 | NOVEL ORGANOSILICA COMPOUNDS | UNIV GENT (BE) | 2018-09-26 | — | — | EP | disclosed |
| US-9181282-B2 | Organosilica compounds | UNIVERSITEIT GENT (BE) | 2015-11-10 | — | — | US | disclosed |
| US-20150005525-A1 | NOVEL ORAGNOSILICA COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-01 | — | — | US | disclosed |
| EP-2794621-A1 | NOVEL ORGANOSILICA COMPOUNDS | Universiteit Gent (BE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013093022-A1 | NOVEL ORGANOSILICA COMPOUNDS | UNIVERSITEIT GENT (BE) | 2013-06-27 | — | — | WO | disclosed |
| US-7402645-B2 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20070155923-A1 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005525-A1 | NOVEL ORAGNOSILICA COMPOUNDS | ORC3, ORMDL3, OR10J3 | TP53 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.