SCHEMBL5034672

SCHEMBL5034672

O=c1ccc2c([S+](c3ccccc3)c3ccccc3)cccc2o1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.46
KCNA3 P22001 1/20 0.44
CA12 O43570 3/20 0.43
CA1 P00915 3/20 0.43
CA9 Q16790 3/20 0.43
CA2 P00918 2/20 0.43
CA3 P07451 2/20 0.43
CA4 P22748 2/20 0.43
CA5A P35218 2/20 0.43
CA7 P43166 2/20 0.43
CA14 Q9ULX7 2/20 0.43
CA5B Q9Y2D0 2/20 0.43
LMNA P02545 1/20 0.43
CA6 P23280 1/20 0.43
MCL1 Q07820 1/20 0.43
SOST Q9BQB4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP3A4 P08684 3/20 0.40
NQO1 P15559 1/20 0.40
NCOA1 Q15788 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3517315 0.91 CYP2A6 (0.40) CYP2A6KCNA3CA12CA1CA9
Trifluoromethanesulfonic Acid SCHEMBL3520616 0.87 CYP2A6 (0.37) CYP2A6KCNA3CA12CA1CA9
SCHEMBL3517596 0.84 CYP2A6 (0.38) CYP2A6KCNA3CA12CA1CA9
SCHEMBL3522616 0.81 KCNA3 (0.33) CYP2A6KCNA3
SCHEMBL15842295 0.70 CA9 (0.53) CYP2A6KCNA3CA12CA1CA9
SCHEMBL5542888 0.69 CYP2A6 (0.56) CYP2A6KCNA3CA12CA1CA9
SCHEMBL5038854 0.68 DRD4 (0.54) CA12CA1CA9CA2CA3
SCHEMBL11035090 0.67 CYP2A6 (0.55) CYP2A6KCNA3CA12CA1CA9
SCHEMBL450134 0.67 CA12 (0.60) CYP2A6KCNA3CA12CA1CA9
SCHEMBL15842364 0.67 CYP2A6 (0.55) CYP2A6KCNA3CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-B1 HETEROCYCLE-BEARING ONIUM SALTS WAKO PURE CHEM IND LTD (JP) 2008-12-31 EP disclosed
EP-1953149-A2 A heterocycle-containing onium salt Wako Pure Chemical Industries, Ltd. (JP) 2008-08-06 EP disclosed