SCHEMBL5034849

SCHEMBL5034849

O=C(O)c1ccc2c(c1)C(=O)c1ccc(O)c(O)c1C2=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 10/20 0.70
MAPT P10636 5/20 0.62
MEN1 O00255 4/20 0.62
HPGD P15428 4/20 0.62
KMT2A Q03164 4/20 0.62
KDM4E B2RXH2 4/20 0.62
ALDH1A1 P00352 3/20 0.62
CYP3A4 P08684 3/20 0.62
ALOX15 P16050 3/20 0.62
RECQL P46063 3/20 0.62
HSD17B10 Q99714 3/20 0.62
MAOA P21397 2/20 0.62
APEX1 P27695 2/20 0.62
MAPK1 P28482 2/20 0.62
ALOX12 P18054 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
BCL2 P10415 1/20 0.62
DAPK1 P53355 1/20 0.62
MCL1 Q07820 1/20 0.62
CYP1B1 Q16678 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3976640 0.86 TTR (0.73) TTRMAPTMEN1HPGDKMT2A
SCHEMBL31436146 0.86 TTR (0.73) TTRMAPTMEN1HPGDKMT2A
SCHEMBL26187220 0.83 TTR (1.00) TTRMAPTMEN1HPGDKMT2A
SCHEMBL31436145 0.82 TTR (0.88) TTRMAPTMEN1HPGDKMT2A
SCHEMBL598301 0.82 TTR (0.88) TTRMAPTMEN1HPGDKMT2A
SCHEMBL71021 0.82 TTR (0.88) TTRMAPTMEN1HPGDKMT2A
SCHEMBL10951857 0.81 TTR (0.58) TTRMAPTMEN1HPGDKMT2A
SCHEMBL9350283 0.81 TTR (0.76) TTRMAPTMEN1HPGDKMT2A
SCHEMBL1495097 0.80 TTR (1.00) TTRMAPTMEN1HPGDKMT2A
SCHEMBL13064957 0.80 TTR (0.74) TTRMAPTMEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59078233-A None JP disclosed
CN-101302326-B Flame-retardant resin composition CHANGCHUN ARTIFICIAL RESIN FACTORY CO LTD 2010-09-08 CN disclosed
CN-101302326-A Flame-retardant resin composition CHANGCHUN ARTIFICIAL RESIN FAC (CN) 2008-11-12 CN disclosed
US-20080262127-A1 FLAME RESISTANT RESIN COMPOSITION CHANG CHUN PLASTICS CO., LTD. (TW) 2008-10-23 US disclosed
JP-S5978233-A PRODUCTION OF POLYESTER TEIJIN LTD 1984-05-07 JP disclosed