Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.55 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037428 | 0.94 | ADORA1 (0.58) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL5034075 | 0.85 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL4803330 | 0.83 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL3944320 | 0.81 | ADORA1 (0.57) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL4805994 | 0.81 | ADORA1 (0.68) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL5034543 | 0.80 | ADORA1 (0.58) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL5032115 | 0.80 | ADORA1 (0.56) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL5034049 | 0.80 | ADORA1 (0.56) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL4800660 | 0.79 | ADORA1 (0.61) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL4808472 | 0.78 | ADORA1 (0.59) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883646-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006125190-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | disclosed |