⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16940588 | 1.00 | — | — | |
| SCHEMBL29991647 | 0.78 | — | — | |
| SCHEMBL13419040 | 0.78 | — | — | |
| SCHEMBL17875360 | 0.77 | — | — | |
| SCHEMBL1085725 | 0.76 | — | — | |
| SCHEMBL4822585 | 0.76 | — | — | |
| SCHEMBL1085727 | 0.76 | — | — | |
| SCHEMBL7044276 | 0.74 | — | — | |
| SCHEMBL11574754 | 0.74 | — | — | |
| SCHEMBL1521347 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260360-B | Copolymerization method of ethylene and terminal alkenyl silane/siloxane, copolymer and application thereof | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-115260357-B | Copolymerization method of olefin-terminal alkenyl silane/siloxane spherical or spheroid copolymer and copolymer | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116217759-A | Coordination precipitation polymerization method for olefin polymerization and obtained polyolefin | 中国石油化工股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116199806-A | Coordination precipitation polymerization method for olefin polymerization and obtained polyolefin | 中国石油化工股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-115260360-A | Copolymerization method of ethylene and terminal alkenyl silane/siloxane, copolymer and application thereof | 中国石油化工股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115260357-A | Copolymerization method of spherical or spheroidal copolymer of olefin-terminal alkenylsilane/siloxane and copolymer | 中国石油化工股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| US-9765048-B2 | Organocatalytic process for asymmetric synthesis of decanolides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-09-19 | — | — | US | disclosed |
| US-20160272608-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-09-22 | — | — | US | disclosed |
| EP-1628974-A4 | HYDANTOIN DERIVATIVES AS INHIBITORS OF TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME (TACE) | BRISTOL MYERS SQUIBB CO (US) | 2008-05-07 | — | — | EP | disclosed |
| US-7132432-B2 | Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-07 | — | — | US | disclosed |
| EP-1628974-A2 | HYDANTOIN DERIVATIVES AS INHIBITORS OF TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME (TACE) | Bristol-Myers Squibb Company (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108086-A2 | HYDANTOIN DERIVATIVES AS INHIBITORS OF TUMOR NECROSIS FACTOR-α CONVERTING ENZYME (TACE) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |
| US-20040254231-A1 | Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE) | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-16 | — | — | US | disclosed |