SCHEMBL5035157

SCHEMBL5035157

CCC(C)(C)c1ccc(Oc2ccccc2C(=O)OC)c(C(C)(C)CC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 7/20 0.50
SMN1; SMN2 Q16637 7/20 0.50
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
MAPK1 P28482 5/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPT P10636 6/20 0.41
HTT P42858 4/20 0.41
UBE2N P61088 2/20 0.41
MITF O75030 1/20 0.41
HSP90AA1 P07900 2/20 0.41
SLC6A3 Q01959 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
ATM Q13315 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5030934 0.88 NPSR1 (0.52) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL9137799 0.86 MEN1 (0.48) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL8377774 0.84 MAPK1 (0.49) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL9141342 0.84 SMN1; SMN2 (0.46) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL2449720 0.81 NPSR1 (0.55) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL9139543 0.80 NPSR1 (0.44) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL9141082 0.77 POLB (0.52) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL9140557 0.77 KMT2A (0.44) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL9316818 0.77 NPSR1 (0.51) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL9140277 0.77 MAPK1 (0.51) NPSR1SMN1; SMN2MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7459263-B2 Optical recording media with triplet-sensitized isomerization EASTMAN KODAK COMPANY (US) 2008-12-02 US disclosed
US-20050136357-A1 Optical recording media with triplet-sensitzed isomerization FPC INC. 2005-06-23 US disclosed