Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036555 | 0.91 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL5041662 | 0.89 | EDNRA (0.74) | EDNRAEDNRB | |
| SCHEMBL5039396 | 0.89 | EDNRA (0.74) | EDNRAEDNRB | |
| SCHEMBL5035360 | 0.89 | EDNRA (0.85) | EDNRAEDNRB | |
| SCHEMBL5039329 | 0.88 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL5035386 | 0.88 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL7849626 | 0.88 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL5039394 | 0.87 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL5032758 | 0.87 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL5035273 | 0.87 | EDNRA (0.78) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149091-B1 | 4-(HETEROCYCLYLSULFONAMIDO)-5-METHOXY-6-(2-METHOXYPHENOXY)-2-PHENYL- OR PYRIDYLPYRIMIDINES AS ENDOTHELIN RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-03-19 | — | — | EP | claimed |