Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 3/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.43 |
| ▸ | SELE | P16581 | 2/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035380 | 0.86 | ICAM1 (0.46) | NMT1ICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL5032100 | 0.86 | ICAM1 (0.48) | NMT1ICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL5210758 | 0.83 | ICAM1 (0.49) | NMT1ICAM1SELEVCAM1L3MBTL1 | |
| SCHEMBL5211159 | 0.78 | NPSR1 (0.52) | ICAM1SELEVCAM1L3MBTL1TDP1 | |
| SCHEMBL10514815 | 0.72 | EDNRA (0.52) | NMT1L3MBTL1TDP1KDM4ENPC1 | |
| SCHEMBL5219829 | 0.71 | EDNRA (0.54) | ICAM1SELEVCAM1L3MBTL1TDP1 | |
| SCHEMBL12553302 | 0.71 | NMT1 (0.45) | NMT1ALDH1A1MEN1KMT2A | |
| SCHEMBL6020201 | 0.71 | KMT2A (0.51) | PDE4BKMT2ADYRK1A | |
| SCHEMBL6021010 | 0.71 | KMT2A (0.51) | PDE4BKMT2ADYRK1A | |
| SCHEMBL4768114 | 0.71 | KMT2A (0.51) | PDE4BKMT2ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585745-A4 | FC RECEPTOR MODULATING COMPOUNDS AND COMPOSITIONS | TRILLIUM THERAPEUTICS INC (CA) | 2008-07-09 | — | — | EP | disclosed |
| EP-1585745-A1 | FC RECEPTOR MODULATING COMPOUNDS AND COMPOSITIONS | Arthron Limited (AU) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004058747-A1 | FC RECEPTOR MODULATING COMPOUNDS AND COMPOSITIONS | ARTHRON LIMITED (AU) | 2004-07-15 | — | — | WO | disclosed |