SCHEMBL5035446

SCHEMBL5035446

COCCOCCC1(CCOCCOC)c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.43
PDK2 Q15119 3/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.33
AR P10275 1/20 0.33
CA2 P00918 1/20 0.33
ITGA4 P13612 1/20 0.32
MAP2K7 O14733 1/20 0.32
CDC25A P30304 1/20 0.32
CDC25B P30305 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MALT1 Q9UDY8 1/20 0.31
ADRB2 P07550 1/20 0.31
POLB P06746 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30960418 1.00 APEX1 (0.43) APEX1PDK2ALDH1A1MAPTSMN1; SMN2
SCHEMBL2142864 1.00 APEX1 (0.43) APEX1PDK2ALDH1A1MAPTSMN1; SMN2
SCHEMBL30960419 1.00 APEX1 (0.43) APEX1PDK2ALDH1A1MAPTSMN1; SMN2
SCHEMBL12624292 0.89 PDK2 (0.39) APEX1PDK2AR
SCHEMBL5329061 0.89 APEX1 (0.48) APEX1PDK2ALDH1A1MAPTSMN1; SMN2
SCHEMBL30004248 0.89 APEX1 (0.48) APEX1PDK2ALDH1A1MAPTSMN1; SMN2
SCHEMBL25133482 0.88 PDK2 (0.41) APEX1PDK2ALDH1A1MAPTSMN1; SMN2
SCHEMBL14287922 0.88 PDK2 (0.41) APEX1PDK2ALDH1A1MAPTSMN1; SMN2
SCHEMBL20872082 0.87 PDK2 (0.40) APEX1PDK2ALDH1A1MAPTSMN1; SMN2
SCHEMBL20872220 0.87 PDK2 (0.40) APEX1PDK2ALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11258017-B2 Semiconducting compositions comprising semiconducting polymers Wuhan Xinqu Chuangrou Optoelectronics Technology Co., Ltd (CN) 2022-02-22 US disclosed
US-20190131533-A1 SEMICONDUCTING COMPOSITIONS COMPRISING SEMICONDUCTING POLYMERS SILVERRAY LTD. (GB) 2019-05-02 US disclosed
US-7442421-B2 Electroluminescent materials and methods of manufacture and use 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-28 US disclosed
US-20070237983-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M INNOVATIVE PROPERTIES COMPANY 2007-10-11 US disclosed
US-7241512-B2 Light emitting polymers including a plurality of arylene monomeric units and a plurality of soft segment end caps, side chains and/or internal units 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-10 US disclosed
EP-1497393-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M Innovative Properties Company (US) 2005-01-19 EP disclosed
US-20030224205-A1 Electroluminescent materials and methods of manufacture and use 3M INNOVATIVE PROPERTIES COMPANY 2003-12-04 US disclosed
WO-2003089542-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-10-30 WO disclosed
EP-0885461-B1 POLYFLUORENES AS MATERIALS FOR PHOTOLUMINESCENCE AND ELECTROLUMINESCENCE DUPONT DISPLAYS INC (US) 2003-08-13 EP disclosed
US-5900327-A LIGHT EMITTING SOLID STATE DEVICE UNIAX CORPORATION (US) 1999-05-04 US disclosed
EP-0885461-A1 POLYFLUORENES AS MATERIALS FOR PHOTOLUMINESCENCE AND ELECTROLUMINESCENCE UNIAX CORPORATION (US) 1998-12-23 EP disclosed
WO-1997033323-A1 POLYFLUORENES AS MATERIALS FOR PHOTOLUMINESCENCE AND ELECTROLUMINESCENCE UNIAX CORPORATION (US) 1997-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11258017-B2 Semiconducting compositions comprising semiconducting polymers PARG, PUF60, PARN APEX1 1037/4885PDK2 3904/4885ALDH1A1 4496/4885
US-20190131533-A1 SEMICONDUCTING COMPOSITIONS COMPRISING SEMICONDUCTING POLYMERS PARG, PUF60, PARN APEX1 1037/4885PDK2 3904/4885ALDH1A1 4496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.