Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842446 | 1.00 | CXCR2 (0.52) | CXCR2CX3CR1 | |
| SCHEMBL6299700 | 0.90 | CXCR2 (0.65) | CXCR2CX3CR1 | |
| SCHEMBL841836 | 0.88 | CXCR2 (0.49) | CXCR2CX3CR1 | |
| SCHEMBL5951044 | 0.75 | CXCR2 (0.80) | CXCR2CX3CR1 | |
| SCHEMBL4497730 | 0.73 | CXCR2 (0.56) | CXCR2CX3CR1 | |
| SCHEMBL5443981 | 0.69 | CXCR2 (0.78) | CXCR2CX3CR1 | |
| SCHEMBL843316 | 0.68 | CXCR2 (0.68) | CXCR2CX3CR1 | |
| SCHEMBL842707 | 0.67 | CXCR2 (0.79) | CXCR2CX3CR1 | |
| SCHEMBL842708 | 0.67 | CXCR2 (0.79) | CXCR2CX3CR1 | |
| SCHEMBL842783 | 0.67 | CXCR2 (0.81) | CXCR2CX3CR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348709-B1 | Thiazolo[4,5-d]pyrimidine compounds for the treatment of rheumatoid arthritis | ASTRAZENECA UK LTD (GB) | 2008-01-16 | — | — | EP | disclosed |
| EP-1222195-B1 | NOVEL THIAZOLO(4,5-D)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LTD (GB) | 2004-01-14 | — | — | EP | disclosed |