SCHEMBL5036367

SCHEMBL5036367

NNC(=O)Cc1ccc(CNC(=O)OCC2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
EPHX2 P34913 1/20 0.46
MAPT P10636 1/20 0.42
ITGB3 P05106 1/20 0.41
ITGAV P06756 1/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
NPC1 O15118 1/20 0.40
OPRD1 P41143 1/20 0.39
FABP7 O15540 1/20 0.39
FABP5 Q01469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5036302 0.88 KMT2A (0.52) KMT2AEPHX2ALDH1A1OPRD1FABP7
SCHEMBL525564 0.86 KMT2A (0.59) KMT2AEPHX2ITGB3ITGAVOPRD1
SCHEMBL30640436 0.86 KMT2A (0.59) KMT2AEPHX2ITGB3ITGAVOPRD1
SCHEMBL14485271 0.85 KMT2A (0.59) KMT2AEPHX2OPRD1FABP7FABP5
SCHEMBL31010055 0.85 KMT2A (0.55) KMT2AEPHX2OPRD1FABP7FABP5
SCHEMBL2057615 0.85 KMT2A (0.55) KMT2AEPHX2OPRD1FABP7FABP5
SCHEMBL3177417 0.85 KMT2A (0.62) KMT2AEPHX2OPRD1FABP7FABP5
Hydrochloric Acid SCHEMBL14485267 0.84 KMT2A (0.57) KMT2AEPHX2OPRD1FABP7FABP5
SCHEMBL2744319 0.84 KMT2A (0.55) KMT2AEPHX2OPRD1FABP7FABP5
SCHEMBL31652901 0.84 KMT2A (0.56) KMT2AEPHX2OPRD1FABP7FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1896086-A1 HYDRAZIDE CONJUGATES AS IMAGING AGENTS Bristol-Myers Squibb Pharma Company (US) 2008-03-12 EP disclosed
US-20070014721-A1 Hydrazide conjugates as imaging agents LANTHEUS MEDICAL IMAGING, INC. 2007-01-18 US disclosed
US-20070014721-A1 Hydrazide conjugates as imaging agents LANTHEUS MEDICAL IMAGING, INC. 2007-01-18 US disclosed
US-20070014721-A1 Hydrazide conjugates as imaging agents LANTHEUS MEDICAL IMAGING, INC. 2007-01-18 US disclosed
WO-2007005491-A1 HYDRAZIDE CONJUGATES AS IMAGING AGENTS BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2007-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070014721-A1 Hydrazide conjugates as imaging agents CA14, CA13, CA1 KMT2A 2223/4885EPHX2 675/4885MAPT 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.