Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277815 | 0.60 | — | — | |
| SCHEMBL1199564 | 0.58 | — | — | |
| SCHEMBL9847743 | 0.57 | GSK3A (0.40) | GSK3AGSK3B | |
| SCHEMBL10790767 | 0.57 | GSK3A (0.46) | GSK3AGSK3B | |
| SCHEMBL366153 | 0.56 | GSK3A (0.71) | GSK3AGSK3B | |
| SCHEMBL353266 | 0.54 | GSK3A (0.42) | GSK3AGSK3B | |
| SCHEMBL12505051 | 0.54 | GSK3A (0.42) | GSK3AGSK3B | |
| SCHEMBL16093525 | 0.54 | — | — | |
| SCHEMBL14703233 | 0.52 | — | — | |
| SCHEMBL9527717 | 0.52 | GSK3A (0.46) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730082-A | Synthesis of substituted tricyclic amides and analogs thereof | 爱彼特生物制药公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117730082-A | Synthesis of substituted tricyclic amides and analogs thereof | 爱彼特生物制药公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115087486-A | Substituted bicyclic and tricyclic ureas and amides, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2022-09-20 | — | — | CN | disclosed |
| EP-1667982-A4 | ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1667982-A2 | ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030791-A2 | ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2005-04-07 | — | — | WO | disclosed |