Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.41 |
| ▸ | HTR2C | P28335 | 7/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MTTP | P55157 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037419 | 1.00 | MCHR1 (0.41) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL3590895 | 0.93 | TRPV1 (0.43) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL3590891 | 0.93 | TRPV1 (0.43) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL13544279 | 0.91 | MCHR1 (0.42) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL3588305 | 0.89 | MCHR1 (0.38) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL3588308 | 0.89 | MCHR1 (0.38) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL5037289 | 0.88 | MCHR1 (0.40) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL13544289 | 0.85 | MCHR1 (0.38) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL13544280 | 0.84 | MEN1 (0.42) | MCHR1HTR2CTRPV1NPC1RAB9A | |
| SCHEMBL3587387 | 0.84 | BRAF (0.40) | MCHR1HTR2CTRPV1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954132-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007100758-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-09-07 | — | — | WO | claimed |