Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 7/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 7/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.77 |
| ▸ | PGR | P06401 | 4/20 | 0.77 |
| ▸ | AR | P10275 | 3/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | APEX1 | P27695 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beclomethasone SCHEMBL5037570 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL7755941 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL1462741 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL18762039 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL13046625 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL8809468 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL3183 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL7614763 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL5486743 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA | |
| Beclomethasone SCHEMBL5486747 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4NR3C1NFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143950-B1 | TOPICAL APPLICATION PRODUCTS AGAINST ONYCHOMYCOSES | BIOEQUAL AG (CH) | 2005-03-09 | — | — | EP | claimed |
| EP-1680076-B1 | PHARMACEUTICAL AND COSMETIC FORMULATIONS FOR TREATING FINGERNAILS | BIOEQUAL AG (CH) | 2008-07-02 | — | — | EP | disclosed |
| US-20070166249-A1 | Pharmaceutical and cosmetic formulations for treating fingernails | BIOEQUAL AG (CH) | 2007-07-19 | — | — | US | disclosed |
| EP-1143950-B1 | TOPICAL APPLICATION PRODUCTS AGAINST ONYCHOMYCOSES | BIOEQUAL AG (CH) | 2005-03-09 | — | — | EP | disclosed |
| US-6740326-B1 | WATER-FREE TOPICAL APPLICATION COMPOSITION FOR TREATMENT OF NAIL DISEASES AND NAIL CARE CONSISTING OF ANTIMYCOTIC AGENT AND LOWER ALKYL ESTER OF LACTIC ACID, MALIC ACID, TARTARIC ACID OR CITRIC ACID AS PENETRATION PROMOTING CARRIER | BIOEQUAL AG (CH) | 2004-05-25 | — | — | US | disclosed |
| EP-0902789-B1 | ANDROSTENE DERIVATIVES | SOFT DRUGS INC (US) | 2002-01-23 | — | — | EP | disclosed |
| US-4377575-A | Corticoid-17-(alkyl carbonates) and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-22 | — | — | US | disclosed |
| EP-0000742-B1 | CORTICOIDS-17-ALKYLCARBONATES, PROCESS FOR THEIR PREPARATION AND PREPARATIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | disclosed |
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| EP-0004975-A2 | 17-Alkylcarbonates of corticoids, process for their preparation and their use as medicines against dermatoses | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-31 | — | — | EP | disclosed |
| EP-0000742-A1 | Corticoids-17-alkylcarbonates, process for their preparation and preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-21 | — | — | EP | disclosed |
| US-4024131-A | ANTIINFLAMMATORY | PLURICHEMIE ANSTALT (FL) | 1977-05-17 | — | — | US | disclosed |