Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 18/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 17/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037818 | 0.93 | MEN1 (0.59) | MEN1KMT2AKDM4E | |
| SCHEMBL5043027 | 0.90 | MEN1 (0.60) | MEN1KMT2AKDM4E | |
| SCHEMBL5034037 | 0.85 | MEN1 (0.64) | MEN1KMT2AKDM4E | |
| SCHEMBL1604971 | 0.84 | MEN1 (0.49) | MEN1KMT2AKDM4EHTR2B | |
| SCHEMBL1604737 | 0.81 | MEN1 (0.50) | MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL1921562 | 0.80 | KDM4E (0.51) | MEN1KMT2AKDM4E | |
| SCHEMBL1604873 | 0.78 | MEN1 (0.53) | MEN1KMT2AKDM4E | |
| SCHEMBL1604871 | 0.78 | MEN1 (0.52) | MEN1KMT2AKDM4E | |
| SCHEMBL5037731 | 0.78 | MEN1 (0.55) | MEN1KMT2AKDM4E | |
| SCHEMBL12710412 | 0.77 | KDM4E (0.72) | MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622914-A4 | NEW PIPERIDINYLAMINO-THIENO 2,3-D PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1797099-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | Epix Delaware, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034511-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| EP-1622914-A2 | NEW PIPERIDINYLAMINO-THIENO 2,3-D PYRIMIDINE COMPOUNDS | Predix Pharmaceuticals Holdings, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004089312-A2 | NEW PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | PREDIX PHARMACEUTICALS HOLDINGS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |