Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038678 | 1.00 | TSHR (0.42) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL9615770 | 0.81 | TSHR (0.55) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL576505 | 0.75 | — | — | |
| SCHEMBL31688091 | 0.73 | TSHR (0.46) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL31688088 | 0.73 | TSHR (0.46) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL969351 | 0.73 | — | — | |
| SCHEMBL31688063 | 0.71 | TSHR (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL1614632 | 0.71 | TSHR (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL4969274 | 0.71 | TSHR (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL1614629 | 0.71 | TSHR (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371901-B2 | Process for the preparation of alkynols | DSM IP ASSETS B.V. (NL) | 2008-05-13 | — | — | US | disclosed |
| US-7371901-B2 | Process for the preparation of alkynols | DSM IP ASSETS B.V. (NL) | 2008-05-13 | — | — | US | disclosed |
| EP-1673327-B1 | PROCESS FOR THE PREPARATION OF ALKYNOLS | DSM IP ASSETS BV (NL) | 2008-01-16 | — | — | EP | disclosed |
| US-20070276150-A1 | Process for the Preparation of Alkynols | DSM IP ASSETS B.V. (NL) | 2007-11-29 | — | — | US | disclosed |
| US-20070276150-A1 | Process for the Preparation of Alkynols | DSM IP ASSETS B.V. (NL) | 2007-11-29 | — | — | US | disclosed |
| EP-1673327-A1 | PROCESS FOR THE PREPARATION OF ALKYNOLS | DSM IP Assets B.V. (NL) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005040076-A1 | PROCESS FOR THE PREPARATIN OF ALKYNOLS | DSM IP ASSETS B.V. (NL) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276150-A1 | Process for the Preparation of Alkynols | HACL2, CYP2S1, SGMS1 | TSHR 2825/4885CHRM2 178/4885CHRM4 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.