Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.34 |
| ▸ | FEN1 | P39748 | 5/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038731 | 1.00 | F10 (0.45) | F10KLKB1ALOX5APFEN1MKNK1 | |
| Acetic Acid SCHEMBL5041605 | 0.97 | F10 (0.43) | F10KLKB1ALOX5APFEN1MKNK1 | |
| SCHEMBL5042821 | 0.90 | F10 (0.47) | F10KLKB1MKNK1MKNK2ST14 | |
| Hydrochloric Acid SCHEMBL5041653 | 0.89 | F10 (0.48) | F10KLKB1MKNK1MKNK2ST14 | |
| SCHEMBL5043089 | 0.86 | PDPK1 (0.37) | F10KLKB1ALOX5APFEN1 | |
| SCHEMBL5043086 | 0.86 | PDPK1 (0.37) | F10KLKB1ALOX5APFEN1 | |
| SCHEMBL5037819 | 0.83 | F10 (0.41) | F10KLKB1ALOX5APFEN1MKNK1 | |
| SCHEMBL5037821 | 0.83 | F10 (0.41) | F10KLKB1ALOX5APFEN1MKNK1 | |
| Acetic Acid SCHEMBL5040924 | 0.81 | F10 (0.64) | F10KLKB1ALOX5APFEN1F2 | |
| SCHEMBL5043591 | 0.81 | F10 (0.34) | F10ALOX5APFEN1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | claimed |