Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853074 | 0.84 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12SLC6A4 | |
| SCHEMBL5045610 | 0.82 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12HRH3 | |
| SCHEMBL6715158 | 0.81 | FFAR1 (0.49) | FFAR1FFAR4MMP2MMP12SLC6A4 | |
| SCHEMBL1854069 | 0.81 | FFAR1 (0.41) | FFAR1FFAR4MMP2MMP12SLC6A4 | |
| SCHEMBL1856884 | 0.81 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12HRH3 | |
| SCHEMBL6022059 | 0.81 | FFAR1 (0.45) | FFAR1FFAR4MMP2MMP12SLC6A4 | |
| SCHEMBL1852611 | 0.80 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1851396 | 0.80 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1851808 | 0.80 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL4669842 | 0.80 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |