Dibromomethane

Dibromomethane

SCHEMBL504057

BrCBr.CCCCc1ccncc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
LMNA P02545 2/20 0.53
HTT P42858 2/20 0.53
TSHR P16473 1/20 0.53
HRH1 P35367 2/20 0.50
ALDH1A1 P00352 2/20 0.49
NPC1 O15118 1/20 0.49
MAPT P10636 1/20 0.49
NFKB1 P19838 1/20 0.49
S1PR1 P21453 1/20 0.49
RAB9A P51151 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
LOXL2 Q9Y4K0 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CA2 P00918 2/20 0.44
CA1 P00915 1/20 0.44
HRH4 Q9H3N8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346623 0.93 SMN1; SMN2 (0.57) SMN1; SMN2LMNAHTTTSHRHRH1
Bromide SCHEMBL547143 0.91 SMN1; SMN2 (0.56) SMN1; SMN2LMNAHTTTSHRHRH1
Fluoride SCHEMBL29251977 0.91 SMN1; SMN2 (0.56) SMN1; SMN2LMNAHTTTSHRHRH1
SCHEMBL369568 0.86 HRH1 (0.59) SMN1; SMN2LMNAHTTTSHRHRH1
SCHEMBL25379522 0.84 HRH1 (0.63) SMN1; SMN2LMNAHTTTSHRHRH1
SCHEMBL2956960 0.84 HRH1 (0.63) SMN1; SMN2LMNAHTTTSHRHRH1
SCHEMBL2953743 0.84 HRH1 (0.63) SMN1; SMN2LMNAHTTTSHRHRH1
SCHEMBL2959380 0.84 HRH1 (0.63) SMN1; SMN2LMNAHTTTSHRHRH1
SCHEMBL214898 0.84 HRH1 (0.63) SMN1; SMN2LMNAHTTTSHRHRH1
SCHEMBL25380899 0.84 HRH1 (0.63) SMN1; SMN2LMNAHTTTSHRHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344034-B2 Shape memory materials comprising polyelectrolyte segments Helmholtz-Zentrum Geesthacht Zentrum fuer Material und Kuestenferschung GmbH (DE) 2013-01-01 US disclosed
EP-1981919-B1 SENSOR COMPRISING SHAPE MEMORY MATERIALS WITH POLYELECTROLYTE SEGMENTS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2012-05-02 EP disclosed
US-20120029097-A1 SHAPE MEMORY MATERIALS COMPRISING POLYELECTROLYTE SEGMENTS GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) 2012-02-02 US disclosed
US-20090309258-A1 Shape Memory Polymers and Shape Memory Polymer Compositions Responsive Towards Two Different Stimuli ASAHI POLYSLIDER COMPANY, LIMITED 2009-12-17 US disclosed
US-20090176896-A1 Shape Memory Materials Comprising Polyelectrolyte Segments GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) 2009-07-09 US disclosed
EP-1981919-A1 SHAPE MEMORY MATERIALS COMPRISING POLYELECTROLYTE SEGMENTS Mnemoscience GmbH (DE) 2008-10-22 EP disclosed
EP-1981695-A1 SHAPE MEMORY POLYMERS AND SHAPE MEMORY POLYMER COMPOSITIONS RESPONSIVE TOWARDS TWO DIFFERENT STIMULI Mnemoscience GmbH (DE) 2008-10-22 EP disclosed
EP-1837160-A1 Ionic strength sensitive shape memory polymers and compositions Mnemoscience GmbH (DE) 2007-09-26 EP disclosed
WO-2007090687-A1 SHAPE MEMORY MATERIALS COMPRISING POLYELECTROLYTE SEGMENTS MNEMOSCIENCE GMBH (DE) 2007-08-16 WO disclosed
WO-2007090685-A1 SHAPE MEMORY POLYMERS AND SHAPE MEMORY POLYMER COMPOSITIONS RESPONSIVE TOWARDS TWO DIFFERENT STIMULI MNEMOSCIENCE GMBH (DE) 2007-08-16 WO disclosed
EP-1818161-A1 Shape memory polymers and shape memory polymer compositions responsive towards two different stimuli Mnemoscience GmbH (DE) 2007-08-15 EP disclosed
EP-1818346-A1 Shape memory materials comprising polyelectrolyte segments Mnemoscience GmbH (DE) 2007-08-15 EP disclosed