Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.63 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041473 | 1.00 | F10 (0.63) | F10PLAUF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL5045863 | 0.99 | F10 (0.65) | F10PLAUF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL5045874 | 0.99 | F10 (0.65) | F10PLAUF2PRSS1PLG | |
| SCHEMBL5045699 | 0.92 | F10 (0.74) | F10PLAUF2PRSS1PLG | |
| SCHEMBL5045716 | 0.92 | F10 (0.74) | F10PLAUF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL5040916 | 0.92 | F10 (0.57) | F10PLAUF2PRSS1LTB4R | |
| Hydrochloric Acid SCHEMBL5040903 | 0.92 | F10 (0.57) | F10PLAUF2PRSS1LTB4R | |
| Hydrochloric Acid SCHEMBL5040992 | 0.91 | F10 (0.56) | F10PLAUF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL5043192 | 0.91 | F10 (0.75) | F10PLAUF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL5041010 | 0.91 | F10 (0.56) | F10PLAUF2PRSS1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |