Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575939 | 0.96 | PTPRC (0.59) | CTSLPTPRCCTSSPTPN13MAOB | |
| SCHEMBL6607479 | 0.92 | MAOB (0.50) | CTSLPTPRCCTSSPTPN13MAOB | |
| SCHEMBL3786936 | 0.83 | PTPRC (0.52) | CTSLPTPRCCTSSPTPN13MAOB | |
| SCHEMBL30799541 | 0.74 | PTPRC (0.91) | CTSLPTPRCCTSSPTPN13MAPT | |
| SCHEMBL69772 | 0.74 | PTPRC (0.91) | CTSLPTPRCCTSSPTPN13MAPT | |
| Anthraquinone SCHEMBL27935127 | 0.71 | MEN1 (0.86) | CTSLPTPRCCTSSPTPN13MAOB | |
| Anthraquinone SCHEMBL28117181 | 0.71 | MEN1 (0.86) | CTSLPTPRCCTSSPTPN13MAOB | |
| Anthraquinone SCHEMBL1901249 | 0.71 | MEN1 (1.00) | PTPRCMAOBNPC1RAB9AMAPT | |
| Anthraquinone SCHEMBL29358690 | 0.71 | MEN1 (1.00) | PTPRCMAOBNPC1RAB9AMAPT | |
| Anthraquinone SCHEMBL14943 | 0.71 | MEN1 (1.00) | PTPRCMAOBNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746406-A | 3, 4-diazafluorenone derivatives, method for synthesizing the same, and electronic device containing the 3, 4-diazafluorenone derivatives | 苏州久显新材料有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-102002003-A | Class I diazafluorenone, fluorene and spiro-fluorene derivative, and preparation method and application thereof | UNIV EAST CHINA NORMAL | 2011-04-06 | — | — | CN | claimed |
| US-20240055657-A1 | AMPHIPHILIC COMPLEXING AGENTS FOR IMPROVED MEMBRANE COMPATIBILITY AND STABILITY OF REDOX SPECIES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2024-02-15 | — | — | US | disclosed |
| CN-110746406-A | 3, 4-diazafluorenone derivatives, method for synthesizing the same, and electronic device containing the 3, 4-diazafluorenone derivatives | 苏州久显新材料有限公司 | 2020-02-04 | — | — | CN | disclosed |
| CN-110746406-A | 3, 4-diazafluorenone derivatives, method for synthesizing the same, and electronic device containing the 3, 4-diazafluorenone derivatives | 苏州久显新材料有限公司 | 2020-02-04 | — | — | CN | disclosed |
| CN-110746406-A | 3, 4-diazafluorenone derivatives, method for synthesizing the same, and electronic device containing the 3, 4-diazafluorenone derivatives | 苏州久显新材料有限公司 | 2020-02-04 | — | — | CN | disclosed |
| US-9663493-B2 | Pyridazine compounds, compositions and methods | NORTHWESTERN UNIVERSITY (US) | 2017-05-30 | — | — | US | disclosed |
| US-9527819-B2 | Pyridazine compounds, compositions and methods | NORTHWESTERN UNIVERSITY | 2016-12-27 | — | — | US | disclosed |
| US-20160326139-A1 | PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS | NORTHWESTERN UNIVERSITY (US) | 2016-11-10 | — | — | US | disclosed |
| US-20150175555-A1 | PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS | NORTHWESTERN UNIVERSITY (US) | 2015-06-25 | — | — | US | disclosed |
| EP-2592075-B1 | PYRIDAZINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | UNIV NORTHWESTERN (US) | 2015-04-29 | — | — | EP | disclosed |
| US-8933076-B2 | Pyridazine compounds, compositions and methods | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-01-13 | — | — | US | disclosed |
| EP-1812408-B1 | PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS | UNIV NORTHWESTERN (US) | 2013-10-09 | — | — | EP | disclosed |
| EP-2592075-A1 | Pyridazine compounds for the treatment of inflammatory diseases | Northwestern University (US) | 2013-05-15 | — | — | EP | disclosed |
| US-8367672-B2 | Pyridazine compounds, compositions and methods | UNIVERSITE DE STRASBOURG (FR) | 2013-02-05 | — | — | US | disclosed |
| US-20120245125-A1 | PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS | UNIVERSITE LOUIS PASTEUR DE STRASBOURG (FR) | 2012-09-27 | — | — | US | disclosed |
| CN-102002003-A | Class I diazafluorenone, fluorene and spiro-fluorene derivative, and preparation method and application thereof | UNIV EAST CHINA NORMAL | 2011-04-06 | — | — | CN | disclosed |
| CN-102002003-A | Class I diazafluorenone, fluorene and spiro-fluorene derivative, and preparation method and application thereof | UNIV EAST CHINA NORMAL | 2011-04-06 | — | — | CN | disclosed |
| US-20080318899-A1 | Pyridazine Compounds, Compositions and Methods | UNIVERSITE DE STRASBOURG (FR) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326139-A1 | PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS | PSEN1, PSEN2, APP | CTSL 4360/4885PTPRC 783/4885CTSS 3397/4885 |
| US-20080318899-A1 | Pyridazine Compounds, Compositions and Methods | APP, PSEN1, PSEN2 | CTSL 4204/4885PTPRC 647/4885CTSS 3249/4885 |
| US-20120245125-A1 | PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS | PSEN1, PSEN2, APP | CTSL 4350/4885PTPRC 780/4885CTSS 3364/4885 |
| US-20150175555-A1 | PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS | PSEN1, PSEN2, APP | CTSL 4360/4885PTPRC 783/4885CTSS 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.