Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.48 |
| ▸ | F2 | P00734 | 10/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | F7 | P08709 | 4/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041911 | 1.00 | F10 (0.48) | F10F2PRSS1F7F3 | |
| Hydrochloric Acid SCHEMBL5041787 | 0.99 | F10 (0.49) | F10F2PRSS1F7F3 | |
| Hydrochloric Acid SCHEMBL5041789 | 0.99 | F10 (0.49) | F10F2PRSS1F7F3 | |
| Hydrochloric Acid SCHEMBL5037769 | 0.89 | F10 (0.48) | F10F2PRSS1F7ST14 | |
| Hydrochloric Acid SCHEMBL5037778 | 0.89 | F10 (0.48) | F10F2PRSS1F7ST14 | |
| Hydrochloric Acid SCHEMBL5041542 | 0.88 | F10 (0.50) | F10F2PRSS1F7ST14 | |
| Hydrochloric Acid SCHEMBL5041547 | 0.88 | F10 (0.50) | F10F2PRSS1F7ST14 | |
| Hydrochloric Acid SCHEMBL5037761 | 0.88 | F10 (0.51) | F10F2PRSS1F7F3 | |
| Hydrochloric Acid SCHEMBL5037754 | 0.88 | F10 (0.51) | F10F2PRSS1F7F3 | |
| Hydrochloric Acid SCHEMBL5045221 | 0.87 | F10 (0.52) | F10F2PRSS1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | claimed |