Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.65 |
| ▸ | F10 | P00742 | 6/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.65 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.56 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.52 |
| ▸ | MASP2 | O00187 | 3/20 | 0.52 |
| ▸ | F7 | P08709 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041975 | 1.00 | F2 (0.65) | F2F10PRSS1TPSAB1ST14 | |
| Hydrochloric Acid SCHEMBL5041998 | 0.99 | F2 (0.64) | F2F10PRSS1TPSAB1ST14 | |
| Hydrochloric Acid SCHEMBL5041988 | 0.99 | F2 (0.64) | F2F10PRSS1TPSAB1ST14 | |
| SCHEMBL5047815 | 0.88 | F2 (0.61) | F2F10PRSS1TPSAB1ST14 | |
| SCHEMBL5047819 | 0.88 | F2 (0.61) | F2F10PRSS1TPSAB1ST14 | |
| SCHEMBL5382862 | 0.87 | F2 (0.63) | F2F10PRSS1TPSAB1ST14 | |
| Hydrochloric Acid SCHEMBL5045157 | 0.86 | F2 (0.60) | F2F10PRSS1TPSAB1ST14 | |
| Hydrochloric Acid SCHEMBL5045156 | 0.86 | F2 (0.60) | F2F10PRSS1TPSAB1ST14 | |
| SCHEMBL12168556 | 0.86 | CA12 (0.61) | F2F10PRSS1 | |
| SCHEMBL12168558 | 0.83 | MEN1 (0.68) | F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |