Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002246 | 1.00 | KCNH2 (0.52) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL5042249 | 1.00 | KCNH2 (0.52) | KCNH2SLC2A1KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL2800136 | 0.99 | KCNH2 (0.52) | KCNH2SLC2A1KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL2800130 | 0.99 | KCNH2 (0.52) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL5039890 | 0.91 | KCNH2 (0.54) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL12000218 | 0.91 | KCNH2 (0.46) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL2798779 | 0.90 | KCNH2 (0.54) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL13235067 | 0.89 | KCNH2 (0.56) | KCNH2SLC2A1KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL2797680 | 0.88 | KCNH2 (0.55) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL13235063 | 0.88 | KCNH2 (0.54) | KCNH2SLC2A1KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| EP-1900732-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |