Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.59 |
| ▸ | CNR2 | P34972 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037543 | 0.74 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4499547 | 0.73 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL6704796 | 0.73 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4508134 | 0.73 | CNR1 (0.81) | CNR1CNR2 | |
| SCHEMBL3364978 | 0.72 | CNR1 (0.81) | CNR1CNR2 | |
| SCHEMBL4215280 | 0.72 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL4496279 | 0.72 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL3364525 | 0.72 | CNR1 (0.81) | CNR1CNR2 | |
| SCHEMBL3363571 | 0.72 | CNR1 (0.81) | CNR1CNR2 | |
| Dimethylamine SCHEMBL1040287 | 0.72 | CNR1 (0.96) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438296-B1 | 1H-IMIDAZOLE DERIVATIVES HAVING CB1 AGONISTIC, CB1 PARTIAL AGONISTIC OR CB1- ANTAGONISTIC ACTIVITY | SOLVAY PHARM BV (NL) | 2008-11-26 | — | — | EP | claimed |