Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5042489 | 1.00 | F2 (0.47) | F2KLKB1F7F3PRSS1 | |
| Hydrochloric Acid SCHEMBL5041799 | 0.99 | F2 (0.46) | F2KLKB1F7F3PRSS1 | |
| Hydrochloric Acid SCHEMBL5041796 | 0.99 | F2 (0.46) | F2KLKB1F7F3PRSS1 | |
| Hydrochloric Acid SCHEMBL5040777 | 0.91 | F2 (0.54) | F2KLKB1PRSS1ERN1PRSS2 | |
| Hydrochloric Acid SCHEMBL5040785 | 0.91 | F2 (0.54) | F2KLKB1PRSS1ERN1PRSS2 | |
| Hydrochloric Acid SCHEMBL5041388 | 0.90 | F2 (0.49) | F2KLKB1F7F3PRSS1 | |
| Hydrochloric Acid SCHEMBL5041383 | 0.90 | F2 (0.49) | F2KLKB1F7F3PRSS1 | |
| SCHEMBL5042056 | 0.90 | F2 (0.49) | F2KLKB1F7PRSS1F10 | |
| SCHEMBL5042049 | 0.90 | F2 (0.49) | F2KLKB1F7PRSS1F10 | |
| Hydrochloric Acid SCHEMBL5045897 | 0.89 | F2 (0.49) | F2KLKB1F7PRSS1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | claimed |