Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.63 |
| ▸ | PPARA | Q07869 | 20/20 | 0.63 |
| ▸ | PPARD | Q03181 | 6/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5042682 | 1.00 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL5042678 | 1.00 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL31095006 | 0.94 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL482387 | 0.94 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL482389 | 0.94 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL482386 | 0.94 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL31094998 | 0.94 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL14206871 | 0.93 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL31095028 | 0.93 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL31095009 | 0.90 | PPARG (0.51) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365207-B2 | Process for the production of chiral propionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2008-04-29 | — | — | US | claimed |
| EP-1670792-B1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2007-12-19 | — | — | EP | claimed |
| US-20070249842-A1 | Process for the production of chiral propionic acid derivatives | PUENTENER KURT | 2007-10-25 | — | — | US | claimed |
| US-7262303-B2 | Process for the production of chiral propionic acid derivatives | HOFFMAN-LA ROCHE INC. (US) | 2007-08-28 | — | — | US | claimed |
| JP-2007506800-A | — | — | 2007-03-22 | — | — | JP | claimed |
| EP-1670792-A1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030764-A1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-04-07 | — | — | WO | claimed |
| US-20050070714-A1 | Process for the production of chiral propionic acid derivatives | HOFFMANN-LA ROCHE INC. | 2005-03-31 | — | — | US | claimed |
| US-7365207-B2 | Process for the production of chiral propionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2008-04-29 | — | — | US | disclosed |
| EP-1670792-B1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2007-12-19 | — | — | EP | disclosed |
| US-20070249842-A1 | Process for the production of chiral propionic acid derivatives | PUENTENER KURT | 2007-10-25 | — | — | US | disclosed |
| US-7262303-B2 | Process for the production of chiral propionic acid derivatives | HOFFMAN-LA ROCHE INC. (US) | 2007-08-28 | — | — | US | disclosed |
| EP-1670792-A1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030764-A1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070714-A1 | Process for the production of chiral propionic acid derivatives | HOFFMANN-LA ROCHE INC. | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070714-A1 | Process for the production of chiral propionic acid derivatives | HRH4, HRH3, HRH1 | PPARG 805/4885PPARA 499/4885PPARD 460/4885 |
| US-20070249842-A1 | Process for the production of chiral propionic acid derivatives | HRH4, HRH3, HRH1 | PPARG 805/4885PPARA 499/4885PPARD 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.