Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 16/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046588 | 0.90 | PTGER2 (0.54) | PTGER2PTGER4 | |
| SCHEMBL5047921 | 0.89 | PTGER2 (0.58) | PTGER2PTGER4TDP1 | |
| SCHEMBL5050457 | 0.87 | PTGER2 (0.48) | PTGER2PTGER4TDP1 | |
| SCHEMBL5048027 | 0.86 | PTGER2 (0.44) | PTGER2PTGER4TDP1 | |
| SCHEMBL5049397 | 0.85 | PTGER2 (0.49) | PTGER2PTGER4TDP1 | |
| SCHEMBL5046825 | 0.85 | PTGER2 (0.60) | PTGER2TDP1 | |
| SCHEMBL5047969 | 0.84 | PTGER2 (0.69) | PTGER2PTGER4 | |
| SCHEMBL6059016 | 0.84 | PTGER2 (0.53) | PTGER2TDP1 | |
| SCHEMBL13398726 | 0.83 | PTGER2 (0.63) | PTGER2PTGER4 | |
| SCHEMBL5048116 | 0.83 | PTGER2 (0.60) | PTGER2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442702-B2 | Treatment of bone disorders; carboxy derivatives | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| EP-1021410-B1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER (US) | 2006-12-27 | — | — | EP | disclosed |
| US-6498172-B1 | (3-(((4-TERT-BUTYL-BENZYL)-(PYRIDINE-3-SULFONYL)-AMINO)-METHYL) -PHENOXY)-ACETIC ACID OR SALT; TREATING SUCH AS OSTEOPOROSIS | PFIZER INC. | 2002-12-24 | — | — | US | disclosed |
| EP-1021410-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999019300-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 1999-04-22 | — | — | WO | disclosed |