Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4533828 | 0.86 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL4538609 | 0.86 | HDAC1 (1.00) | HDAC1KCNH2 | |
| SCHEMBL4541782 | 0.81 | HDAC1 (1.00) | HDAC1KCNH2 | |
| SCHEMBL4541780 | 0.81 | HDAC1 (1.00) | HDAC1KCNH2 | |
| SCHEMBL4541792 | 0.81 | HDAC1 (0.94) | HDAC1 | |
| SCHEMBL4530382 | 0.80 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL8161162 | 0.80 | HDAC1 (0.70) | HDAC1KCNH2 | |
| SCHEMBL4526024 | 0.80 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL2410399 | 0.80 | HDAC1 (0.65) | HDAC1 | |
| SCHEMBL4540246 | 0.79 | HDAC1 (0.83) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945028-A2 | SUBSTITUTED NICOTINAMIDE COMPOUNDS | Merck & Co., Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007055942-A2 | SUBSTITUTED NICOTINAMIDE COMPOUNDS | MERCK & CO., INC. (US) | 2007-05-18 | — | — | WO | disclosed |