Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 10/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 7/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043494 | 1.00 | F10 (0.47) | F10KLKB1MAPK14F2TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5045406 | 0.99 | F10 (0.48) | F10KLKB1MAPK14F2TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5045401 | 0.99 | F10 (0.48) | F10KLKB1MAPK14F2TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5041541 | 0.90 | F10 (0.49) | F10KLKB1F2LOXLOXL2 | |
| Hydrochloric Acid SCHEMBL5041535 | 0.90 | F10 (0.49) | F10KLKB1F2LOXLOXL2 | |
| Hydrochloric Acid SCHEMBL5037788 | 0.88 | F10 (0.54) | F10KLKB1MAPK14F2TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5037782 | 0.88 | F10 (0.54) | F10KLKB1MAPK14F2TMPRSS6 | |
| SCHEMBL6068687 | 0.85 | MAPK14 (0.43) | F10KLKB1MAPK14EPHX2PPARG | |
| Hydrochloric Acid SCHEMBL5045148 | 0.85 | F10 (0.47) | F10KLKB1F2LOXLOXL2 | |
| Hydrochloric Acid SCHEMBL5045137 | 0.85 | F10 (0.47) | F10KLKB1F2LOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |