Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.62 |
| ▸ | OXTR | P30559 | 7/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16550612 | 0.90 | AVPR1A (0.78) | AVPR1AOXTRAVPR2AVPR1BOPRD1 | |
| SCHEMBL28754783 | 0.90 | AVPR1A (0.78) | AVPR1AOXTRAVPR2AVPR1BOPRD1 | |
| SCHEMBL16550611 | 0.90 | AVPR1A (0.78) | AVPR1AOXTRAVPR2AVPR1BOPRD1 | |
| SCHEMBL16550680 | 0.90 | AVPR1A (0.78) | AVPR1AOXTRAVPR2AVPR1BOPRD1 | |
| SCHEMBL24313450 | 0.88 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2 | |
| SCHEMBL5034150 | 0.88 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2 | |
| SCHEMBL5036670 | 0.88 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2 | |
| SCHEMBL4416107 | 0.88 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2 | |
| SCHEMBL29449382 | 0.88 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2 | |
| SCHEMBL5566381 | 0.87 | AVPR1A (0.77) | AVPR1AOXTRAVPR2FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110960495-B | Oral formulations of pyrrolidine derivatives | 奥布赛瓦股份公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114105851-A | Crystals useful in methods of treating disorders associated with OT-R activity | 奥布赛瓦股份公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114105850-A | Crystals useful in methods of treating disorders associated with OT-R activity | 奥布赛瓦股份公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-110960495-A | Oral formulations of pyrrolidine derivatives | 奥布赛瓦股份公司 | 2020-04-07 | — | — | CN | disclosed |
| EP-1390347-B1 | PYRROLIDINE ESTER DERIVATIVES WITH OXYTOCIN MODULATING ACTIVITY | SERONO LAB (CH) | 2008-05-07 | — | — | EP | disclosed |