Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 11/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.38 |
| ▸ | MASP2 | O00187 | 3/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043550 | 1.00 | F10 (0.48) | F10F2ST14F7PRSS1 | |
| Hydrochloric Acid SCHEMBL5043528 | 0.99 | F10 (0.49) | F10F2ST14F7PRSS1 | |
| Hydrochloric Acid SCHEMBL5045476 | 0.99 | F10 (0.49) | F10F2ST14F7PRSS1 | |
| SCHEMBL5042821 | 0.91 | F10 (0.47) | F10F2ST14F7PRSS1 | |
| Hydrochloric Acid SCHEMBL5041653 | 0.90 | F10 (0.48) | F10F2ST14F7PRSS1 | |
| Hydrochloric Acid SCHEMBL5037769 | 0.89 | F10 (0.48) | F10F2ST14F7PRSS1 | |
| Hydrochloric Acid SCHEMBL5037778 | 0.89 | F10 (0.48) | F10F2ST14F7PRSS1 | |
| SCHEMBL5042128 | 0.87 | F10 (0.46) | F10F2ST14F7PRSS1 | |
| SCHEMBL5042119 | 0.87 | F10 (0.46) | F10F2ST14F7PRSS1 | |
| Hydrochloric Acid SCHEMBL5041547 | 0.86 | F10 (0.50) | F10F2ST14F7PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | claimed |
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | claimed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | claimed |
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |