Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | ITK | Q08881 | 2/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039184 | 0.93 | NR1H2 (0.37) | NR1H2BRD4CREBBPNR1H3 | |
| SCHEMBL3046620 | 0.90 | NR1H2 (0.35) | NR1H2BRD4CREBBPNR1H3GPR119 | |
| SCHEMBL3044742 | 0.88 | NR1H2 (0.36) | NR1H2MEN1KMT2ANR1H3ITK | |
| SCHEMBL3047535 | 0.87 | NR1H2 (0.35) | NR1H2BRD4CREBBPNR1H3 | |
| SCHEMBL3050173 | 0.87 | NR1H2 (0.37) | NR1H2BRD4CREBBPNR1H3 | |
| SCHEMBL3046659 | 0.86 | NR1H2 (0.44) | NR1H2BRD4CREBBPNR1H3 | |
| SCHEMBL3050351 | 0.85 | NR1H2 (0.38) | NR1H2BRD4CREBBPNR1H3 | |
| SCHEMBL3047044 | 0.85 | NR1H2 (0.40) | NR1H2BRD4CREBBPNR1H3 | |
| SCHEMBL3043856 | 0.85 | NR1H2 (0.38) | NR1H2BRD4CREBBPNR1H3 | |
| SCHEMBL3049380 | 0.85 | NR1H2 (0.36) | NR1H2BRD4CREBBPNR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |