SCHEMBL5044206

SCHEMBL5044206

CC(NC(O)=S)c1ccccc1.NC(O)=S.[Pb]

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HSD17B10 Q99714 2/20 0.47
HTT P42858 1/20 0.46
ATM Q13315 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HDAC6 Q9UBN7 1/20 0.45
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9063455 0.98 MAPT (0.50) MAPTKDM4EALDH1A1HSD17B10HTT
SCHEMBL11749030 0.96 MAPT (0.49) MAPTKDM4EALDH1A1HSD17B10HTT
SCHEMBL27773043 0.92 HSD17B10 (0.53) MAPTKDM4EALDH1A1HSD17B10HTT
SCHEMBL11271172 0.88 MAPT (0.47) MAPTKDM4EALDH1A1HSD17B10HTT
SCHEMBL5530166 0.84 MAPT (0.55) MAPTKDM4EALDH1A1HSD17B10HTT
SCHEMBL4037544 0.84 MAPT (0.55) MAPTKDM4EALDH1A1HSD17B10HTT
SCHEMBL28581079 0.79 MAPT (0.41) MAPTKDM4EALDH1A1HSD17B10HTT
Zinc Ion SCHEMBL2921239 0.78 MAPT (0.47) MAPTKDM4EALDH1A1HSD17B10HTT
SCHEMBL28527565 0.78 HSD17B10 (0.52) MAPTKDM4EALDH1A1HSD17B10HTT
SCHEMBL13810445 0.78 HSD17B10 (0.52) MAPTKDM4EALDH1A1HSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166356-B Method for producing polyurethane compositions 巴斯夫欧洲公司 2023-12-29 CN disclosed
US-20210380750-A1 PROCESS FOR PRODUCING A POLYURETHANE COMPOSITION BASF SE (DE) 2021-12-09 US disclosed
EP-3887420-A1 PROCESS FOR PRODUCING A POLYURETHANE COMPOSITION BASF SE (DE) 2021-10-06 EP disclosed
CN-113166356-A Process for producing polyurethane composition 巴斯夫欧洲公司 2021-07-23 CN disclosed
WO-2020109366-A1 PROCESS FOR PRODUCING A POLYURETHANE COMPOSITION BASF SE (DE) 2020-06-04 WO disclosed
EP-3023446-A1 Continuous high-throughput process for the preparation of polyurethanes BASF SE (DE) 2016-05-25 EP disclosed
EP-1876195-B1 Polymerization Process ROHM & HAAS (US) 2013-05-01 EP disclosed
EP-1876195-A2 Polymerization Process Rohm and Haas Company (US) 2008-01-09 EP disclosed
US-20070293650-A1 Polymerization process ARCHIBALD VERE ORLAND 2007-12-20 US disclosed
US-7199207-B2 Neutral-coloured 1K polyurethane adhesive HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-04-03 US disclosed
US-20060020101-A1 Low-viscosity polyurethane prepolymers based on 2,4'-MDI BAYER MATERIALSCIENCE AG 2006-01-26 US disclosed
US-20050137377-A1 Neutral-coloured 1K polyurethane adhesive HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2005-06-23 US disclosed