SCHEMBL5044334

SCHEMBL5044334

O=C1CCCN1CCI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5044283 0.87 PIK3CD (0.47)
SCHEMBL9179383 0.86
SCHEMBL261644 0.85 PIK3CD (0.58)
SCHEMBL729385 0.84
SCHEMBL5424673 0.81 PIK3CD (0.54)
SCHEMBL188184 0.81
SCHEMBL730495 0.80 PIK3CD (0.48)
SCHEMBL989008 0.79 PIK3CD (0.52)
SCHEMBL31632694 0.79 PIK3CD (0.52)
SCHEMBL19514132 0.79 PIK3CD (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020112846-A1 SMALL MOLECULE MODULATORS OF SIGMA-1 AND SIGMA-2 RECEPTORS AND USES THEREOF NORTHWESTERN UNIVERSITY (US) 2020-06-04 WO disclosed
EP-2781519-B1 NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME ST PHARM CO LTD (KR) 2019-10-30 EP disclosed
US-9499537-B2 Antiviral pyrrolopyridine derivatives and method for preparing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-11-22 US disclosed
US-9499537-B2 Antiviral pyrrolopyridine derivatives and method for preparing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-11-22 US disclosed
US-9499537-B2 Antiviral pyrrolopyridine derivatives and method for preparing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-11-22 US disclosed
CN-104066732-B Novel antiviral Pyrrolopyridine derivatives and preparation method thereof KOREA CHEMICAL RESEARCH INSTITUTE (KR) 2016-04-13 CN disclosed
EP-2781519-A1 NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME Korea Research Institute of Chemical Technology (KR) 2014-09-24 EP disclosed
EP-2781519-A1 NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME Korea Research Institute of Chemical Technology (KR) 2014-09-24 EP disclosed
CN-104066732-A Novel antiviral pyrrolopyridine derivative and a production method for same KOREA RES INST CHEM TECH 2014-09-24 CN disclosed
US-20140249162-A1 NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2014-09-04 US disclosed
WO-2013073875-A1 NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME 한국화학연구원 (KR) 2013-05-23 WO disclosed
CN-1729152-B Hydroformylation process for the conversion of ethylenically unsaturated compounds to alcohols SHELL INT RESEARCH 2010-05-26 CN disclosed
EP-1572608-B1 HYDROFORMYLATION PROCESS FOR THE CONVERSION OF AN ETHYLENICALLY UNSATURATED COMPOUND TO AN ALCOHOL SHELL INT RESEARCH (NL) 2008-07-02 EP disclosed
US-7208606-B2 Hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol SHELL OIL COMPANY (US) 2007-04-24 US disclosed
US-7186868-B2 Hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol SHELL OIL COMPANY (US) 2007-03-06 US disclosed
US-20070032687-A1 Hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol SHELL USA, INC. 2007-02-08 US disclosed
CN-1729152-A Hydroformylation process for the conversion of ethylenically unsaturated compounds to alcohols SHELL INT RESEARCH (NL) 2006-02-01 CN disclosed
EP-1572608-A1 HYDROFORMYLATION PROCESS FOR THE CONVERSION OF AN ETHYLENICALLY UNSATURATED COMPOUND TO AN ALCOHOL SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2005-09-14 EP disclosed
US-20040152928-A1 Hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol SHELL USA, INC. 2004-08-05 US disclosed
WO-2004054946-A1 HYDROFORMYLATION PROCESS FOR THE CONVERSION OF AN ETHYLENICALLY UNSATURATED COMPOUND TO AN ALCOHOL SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2004-07-01 WO disclosed