⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31176727 | 0.96 | — | — | |
| SCHEMBL6649835 | 0.67 | — | — | |
| Methanesulfonamide SCHEMBL1817 | 0.64 | — | — | |
| SCHEMBL1592582 | 0.64 | — | — | |
| SCHEMBL521787 | 0.64 | — | — | |
| SCHEMBL10912580 | 0.62 | — | — | |
| Sulfamide SCHEMBL5880 | 0.61 | — | — | |
| SCHEMBL24003797 | 0.61 | — | — | |
| SCHEMBL8348898 | 0.61 | — | — | |
| Methanesulfonamide SCHEMBL3282555 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169144-B1 | PROCESS FOR THE PREPARATION OF 7-AMINO AND 7-SUBSTITUTED AMINO-DESACETOXYCEPHALOSPORINS FROM THE CORRESPONDING 6-SUBSTITUTED AMINO PENICILLIN SULPHOXIDES | GEMA S.A. (ES) | 1990-06-06 | — | — | EP | claimed |
| CN-116209433-B | Small molecule albumin binding agents | 俄勒冈健康科学大学 | 2025-05-23 | — | — | CN | disclosed |
| CN-114746095-B | HCK as therapeutic target of MYD88 mutant diseases | 达纳-法伯癌症研究所有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-117580841-A | Macrocyclic compounds and uses thereof | 特修斯制药公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-112384517-B | Heteroaryl compounds and uses thereof | 新旭生技股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116209433-A | Small molecule albumin binding agents | 俄勒冈健康科学大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-115667207-A | Cationic lipids based on phenolic acid lipids | 翻译生物公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-1594505-A4 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1594505-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-11-16 | — | — | EP | disclosed |
| US-6908947-B2 | Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-06-21 | — | — | US | disclosed |
| EP-0861836-B1 | Sulfonamido substituted condensed, seven-membered ring compounds with potassium channel blocking activity | AVENTIS PHARMA GMBH (DE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2004072101-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-08-26 | — | — | WO | disclosed |
| US-20020072514-A1 | Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them | HOECHST AKTIENGESELLSCHAFT | 2002-06-13 | — | — | US | disclosed |
| US-6333349-B1 | POTASSIUM CHANNEL OR THE I.SUB.KS CHANNEL OPENED BY CYCLIC ADENOSINE MONOPHOSPHATE AS POTASSIUM CHANNEL ACTIVATORS AND CARDIOVASCULAR DISORDERS, ANTIARRHYTHMIAS, FOR THE TREATMENT OF ULCERS OF THE GASTROINTESTINAL REGION OR FOR THE TREATMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-12-25 | — | — | US | disclosed |
| EP-0861836-A1 | Sulfonamido substituted condensed, seven-membered ring compounds with potassium channel blocking activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-02 | — | — | EP | disclosed |
| EP-0169144-B1 | PROCESS FOR THE PREPARATION OF 7-AMINO AND 7-SUBSTITUTED AMINO-DESACETOXYCEPHALOSPORINS FROM THE CORRESPONDING 6-SUBSTITUTED AMINO PENICILLIN SULPHOXIDES | GEMA S.A. (ES) | 1990-06-06 | — | — | EP | disclosed |
| US-4767851-A | Process for the preparation of 7-amino and 7-substituted amino-desacetoxycephalosporins | GEMA, S.A. (ES) | 1988-08-30 | — | — | US | disclosed |
| EP-0169144-A2 | Process for the preparation of 7-amino and 7-substituted amino-desacetoxycephalosporins from the corresponding 6-substituted amino penicillin sulphoxides | GEMA S.A. (ES) | 1986-01-22 | — | — | EP | disclosed |
| EP-0043630-B1 | IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS | GIST-BROCADES N.V. (NL) | 1986-01-08 | — | — | EP | disclosed |