Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.75 |
| ▸ | F3 | P13726 | 20/20 | 0.75 |
| ▸ | F10 | P00742 | 9/20 | 0.69 |
| ▸ | F2 | P00734 | 6/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044319 | 0.88 | F7 (0.68) | F7F3F10F2PRSS1 | |
| SCHEMBL5512942 | 0.86 | F7 (1.00) | F7F3F10F2PRSS1 | |
| SCHEMBL3856774 | 0.85 | F7 (0.52) | F7F3F10F2PRSS1 | |
| SCHEMBL5037211 | 0.84 | F7 (0.66) | F7F3F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL5133568 | 0.83 | F7 (0.72) | F7F3F10F2PRSS1 | |
| SCHEMBL14584436 | 0.82 | F7 (0.59) | F7F3F10F2PRSS1 | |
| SCHEMBL4333411 | 0.82 | F7 (0.49) | F7F3F10F2PRSS1 | |
| SCHEMBL7443963 | 0.82 | F7 (0.49) | F7F3F10F2PRSS1 | |
| SCHEMBL8300552 | 0.82 | F7 (0.49) | F7F3F10F2PRSS1 | |
| SCHEMBL5040969 | 0.82 | F7 (0.66) | F7F3F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594505-A4 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7122559-B2 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-17 | — | — | US | disclosed |
| EP-1594505-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-14 | — | — | US | disclosed |
| WO-2004072101-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | F7, SERPINE1, HABP2 | F7 1/4885F3 62/4885F10 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.