⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaldehyde SCHEMBL8145563 | 1.00 | TP53 (0.47) | — | |
| Formic Acid SCHEMBL9619050 | 0.86 | TP53 (0.47) | — | |
| Formic Acid SCHEMBL9619061 | 0.86 | TP53 (0.47) | — | |
| Formic Acid SCHEMBL9619062 | 0.86 | TP53 (0.47) | — | |
| SCHEMBL11267658 | 0.86 | TP53 (0.47) | — | |
| Formic Acid SCHEMBL27452140 | 0.86 | — | — | |
| SCHEMBL2531259 | 0.84 | TP53 (0.61) | — | |
| SCHEMBL405938 | 0.84 | TP53 (0.61) | — | |
| SCHEMBL2774033 | 0.84 | TP53 (0.61) | — | |
| SCHEMBL5940223 | 0.84 | TP53 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2010 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118175990-A | Osmotic formulation composition comprising an acid sensitive ingredient | 奥德森生物有限公司 | 2024-06-11 | — | — | CN | claimed |
| US-8980319-B2 | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans | MALLINCKRODT LLC (US) | 2015-03-17 | — | — | US | claimed |
| US-20140086987-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | MALLINCKRODT LLC (US) | 2014-03-27 | — | — | US | claimed |
| US-8597681-B2 | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans | MALLINCKRODT LLC (US) | 2013-12-03 | — | — | US | claimed |
| US-8529955-B2 | Methods of treatment using a gastric retained gabapentin dosage | DEPOMED, INC. (US) | 2013-09-10 | — | — | US | claimed |
| US-8440232-B2 | Methods of treatment using a gastric retained gabapentin dosage | DEPOMED, INC. (US) | 2013-05-14 | — | — | US | claimed |
| CN-102697704-A | Controlled release formulations of opioid and nonopioid analgesics | ALZA CORP | 2012-10-03 | — | — | CN | claimed |
| US-20120064168-A1 | METHODS OF TREATMENT USING A GASTRIC RETAINED GABEPENTIN DOSAGE | DEPOMED, INC. (US) | 2012-03-15 | — | — | US | claimed |
| US-8119166-B2 | Methods of treatment using a gastric retained gabapentin dosage | DEPOMED, INC. (US) | 2012-02-21 | — | — | US | claimed |
| US-20120027823-A1 | METHODS OF TREATMENT USING A GASTRIC RETAINED GABAPENTIN DOSAGE | DEPOMED, INC. (US) | 2012-02-02 | — | — | US | claimed |
| US-20050064036-A1 | Methods of treatment using a gastric retained gabapentin dosage | ASSERTIO THERAPEUTICS, INC. (F/K/A DEPOMED, INC.) | 2005-03-24 | — | — | US | claimed |
| EP-1502591-A2 | Controlled-release formulations coated with aqueous dispersions of ethylcellulose | EURO-CELTIQUE S.A. (LU) | 2005-02-02 | — | — | EP | claimed |
| US-20040175428-A1 | Controlled release by extrusion of solid amorphous dispersions of drugs | PFIZER INC. | 2004-09-09 | — | — | US | claimed |
| US-20040137156-A1 | Coated solid dosage form and method for preparing same | LEE ERNEST J | 2004-07-15 | — | — | US | claimed |
| US-6706283-B1 | INCREASING BIOAVAILABILITY OF SPARINGLY WATER SOLUBLE ACTIVE INGREDIENTS; CONTROLLED INFLUX OF WATER TO CORE USING NON-DISSOLVING, NONERODING COATING | PFIZER INC | 2004-03-16 | — | — | US | claimed |
| WO-2004010982-A1 | METHOD OF PREPARING SOLID DOSAGE FORMS COATED IN TWO LAYERS COMPRISING A WATER-INSOLUBLE POLYMER AND A WATER-SOLUBLE PORE FORMER | PHARMACIA CORPORATION (US) | 2004-02-05 | — | — | WO | claimed |
| EP-1027888-A2 | Osmotic system for delivery of solid amorphous dispersions of drugs | Pfizer Products Inc. (US) | 2000-08-16 | — | — | EP | claimed |
| US-5458887-A | OF AN OSMOTIC CORE CONTAINING A DRUG AND A WATER SWELLABLE COMPONENT AND A WATER RESISTANT POLYMER COATING CONTAINING A COMPOUND WHICH DISSOLVES IN GASTROINTESTINAL FLUID | ANDRX PHARMACEUTICALS, INC. (US) | 1995-10-17 | — | — | US | claimed |
| EP-0326727-A1 | Sustained release implant and method for preparing same | INTERNATIONAL MINERALS AND CHEMICAL CORPORATION (US) | 1989-08-09 | — | — | EP | claimed |
| US-4761289-A | Sustained release implant and method for preparing same | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1988-08-02 | — | — | US | claimed |