Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.70 |
| ▸ | KLK1 | P06870 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040561 | 0.91 | F10 (0.74) | F10F2KLK1 | |
| SCHEMBL5035767 | 0.90 | F10 (0.76) | F10F2KLK1 | |
| SCHEMBL5040139 | 0.89 | F10 (0.66) | F10F2KLK1 | |
| SCHEMBL3832919 | 0.88 | F10 (0.72) | F10F2KLK1 | |
| SCHEMBL3833104 | 0.88 | F10 (0.69) | F10F2KLK1 | |
| SCHEMBL5038619 | 0.84 | F10 (0.72) | F10F2KLK1 | |
| SCHEMBL6295673 | 0.84 | F10 (0.65) | F10F2KLK1 | |
| SCHEMBL1674936 | 0.83 | F10 (0.77) | F10F2KLK1 | |
| SCHEMBL1455580 | 0.83 | F10 (0.73) | F10F2KLK1 | |
| SCHEMBL1675026 | 0.83 | F10 (0.80) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465806-B2 | Pyrrole-derivatives as factor Xa inhibitors | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-12-16 | — | — | US | claimed |
| EP-1725550-A2 | PYRROLE-DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-11-29 | — | — | EP | claimed |
| WO-2005085239-A2 | PYRROLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-09-15 | — | — | WO | claimed |
| EP-1568698-A1 | Pyrrole-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2005-08-31 | — | — | EP | claimed |
| US-7465806-B2 | Pyrrole-derivatives as factor Xa inhibitors | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-12-16 | — | — | US | disclosed |
| EP-1725550-A2 | PYRROLE-DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005085239-A2 | PYRROLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-09-15 | — | — | WO | disclosed |
| EP-1568698-A1 | Pyrrole-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2005-08-31 | — | — | EP | disclosed |