Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489154 | 0.90 | AURKA (0.80) | AURKAAURKB | |
| SCHEMBL3489865 | 0.89 | AURKA (0.79) | AURKAAURKB | |
| SCHEMBL3488255 | 0.82 | AURKA (0.70) | AURKAAURKB | |
| SCHEMBL3488576 | 0.82 | AURKA (0.69) | AURKAAURKB | |
| SCHEMBL3490186 | 0.81 | AURKA (0.83) | AURKAAURKB | |
| SCHEMBL3490072 | 0.80 | AURKA (0.66) | AURKAAURKB | |
| SCHEMBL5049568 | 0.80 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL3489839 | 0.80 | AURKA (0.66) | AURKAAURKB | |
| SCHEMBL5488458 | 0.80 | AURKA (0.75) | AURKAAURKB | |
| SCHEMBL3490982 | 0.80 | AURKA (0.85) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402585-B2 | Substituted quinazoline derivatives as inhibitors of aurora kinases | ASTRAZENECA AB (SE) | 2008-07-22 | — | — | US | disclosed |