SCHEMBL504658

SCHEMBL504658

Clc1cncc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL362877 0.97
Hydrochloric Acid SCHEMBL29131079 0.97
Cyanide SCHEMBL28048369 0.93 HCAR2 (0.39)
Formaldehyde SCHEMBL28841438 0.93 HCAR2 (0.43)
Formic Acid SCHEMBL28134489 0.87 HCAR2 (0.44)
Formic Acid Methyl Ester SCHEMBL28134488 0.82 HCAR2 (0.36)
SCHEMBL28601517 0.82 KDM4E (0.43)
SCHEMBL197638 0.78
SCHEMBL4974 0.78
Hydrochloric Acid SCHEMBL6069542 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149801-A Deuterated polyhalogen aromatic compound, preparation method thereof and organic intermediate 南京工业大学 2021-07-23 CN claimed
CN-106674200-B A kind of compound and its preparation method and application containing L- prolineamide segment 西安交通大学 2019-04-12 CN claimed
CN-106674200-A Compound containing L-prolinamide fragment, and preparation method and application thereof 西安交通大学 2017-05-17 CN claimed
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 WO disclosed
CN-122070349-A Organic light-emitting compound and organic electroluminescent device comprising the same 索路思高新材料有限公司 2026-05-19 CN disclosed
US-20260132132-A1 3A,4,5,6-TETRAHYDRO-1 H-PYRAZOLO[3,4-C]PYRIDIN-7(7AH)-ONE DERIVATIVES AS FACTOR XIIA INHIBITORS KALVISTA PHARMACEUTICALS LTD (GB) 2026-05-14 US disclosed
EP-4735431-A2 MK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2026-05-06 EP disclosed
WO-2026088070-A1 COMPOUNDS PFIZER INC. (US) 2026-04-30 WO disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2026-03-19 US disclosed
US-12516046-B2 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors MERCK SHARP & DOHME LLC (US) 2026-01-06 US disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5191084-A PHENYL PYRAZOLIDINONES AS BRONCHODILATORS AND ANTI-INFLAMMATORY AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1993-03-02 US disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0511865-A1 Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents AMERICAN HOME PRODUCTS CORPORATION (US) 1992-11-04 EP disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
CN-1007249-B Preparation method of 2-phenyl pyrano [2, 3-b ] pyridine compound MERRELL DOW PHARMA (US) 1990-03-21 CN disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed
CN-85109303-A The 2-phenylpyran is the preparation method of [2,3-b] pyridine compounds and their also 1986-08-20 CN disclosed